Job Market
Seeking for excellent European immunologists? Please send your job offers to hahner@efis.org
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Inserm U700: Physiopathology and Epidemiology of Respiratory Insufficiency
Faculté de Médecine Xavier Bichat in association with Université Paris VII Denis Diderot
Post-Doctoral Position in Paris (France)
We are looking for a post-doctoral candidate for a 3 year joint Academic / Industry project between Inserm Faculty of Medicine and MedImmune Ltd, to start February-March 2012. This innovative project is focused on autoimmunity in Idiopathic Pulmonary Fibrosis (IPF) and is in the group of Pr Bruno Crestani. IPF is a chronic debilitating lung disease which is characterized by excess aberrant matrix deposition in the lung, resulting in impaired gas exchange and ultimately death. There are limited clinical options for these patients, with mortality occurring 2-5 years post-diagnosis. Multiple underlying causes have been associated with IPF and Pr Crestani’s lab has recently demonstrated a link between autoimmunity and IPF disease severity. This novel and exciting project will focus on the mechanisms by which autoimmunity promotes lung fibrosis using in vitro and in vivo models of disease and combining this with characterization of human relevant samples from subjects with IPF, to improve our understanding of this complex and debilitating disease.
The Applicant
We are looking for highly motivated scientists with:
- A PhD in a relevant subject area, preferably specializing in lung research and/ or models of immunology or autoimmunity
– An established understanding of in vitro and in vivo models of lung disease, ideally with experience in fibrosis and/ or autoimmune models
- Strong written and oral communication skills, with a strong track-record of publications in peer-reviewed journal is required.
This position has no nationality restriction and the working language is French and/or English.
Contact
Please send your application with a full CV and a cover letter outlining your motivation, a short summary of your past research and the names of at least two references to: Bruno.crestani@bch.aphp.fr, Valerie.besnard@inserm.fr.
About MedImmune
MedImmune strives to provide better medicines to patients, new medical options for physicians, and rewarding careers to employees. Dedicated to advancing science and medicine to help people live better lives, the company is focused on infection, oncology, respiratory disease and inflammation, cardiovascular/gastrointestinal disease and neuroscience. The company has two marketed products and an advancing pipeline of promising candidates, all designed to treat or prevent a number of debilitating or life-threatening diseases.
STROMA – Marie Curie FP7 Initial Training Network
The ITN – STROMA is currently recruiting 13 PhD students (Early Stage Researchers) and 3 Postdoctoral Scientists (Experienced Researchers) to 12 academic and industrial partner organisations across Europe in the research area of stromal cell – immune cell interactions. Stromal cells create the microenvironment in which the immune system operates, research in this network will analyse the function of stroma in healthy tissues and in diseases including cancer, autoimmune disease, viral, bacterial and parasitic infection. Research and training opportunities will provide participants with experience in state-of-the art multidisciplinary technologies, complementary skills and industrial experience.
To obtain further information about the Postdoc and PhD research opportunities and to apply for the positions on-line please go to the STROMA ITN website:
www.stromal.org
Application deadline for PhD students is the 20th January 2012.
Postdoctoral Position: Laboratory for Dendritic cell biology (DeCiBeL)
Center for Immunology of Marseille-Luminy, Marseille, France
Two funded postdoctoral positions starting end of 2011 are available in the laboratory for Dendritic cell biology of Dr. Philippe PIERRE. These positions have no nationality restriction and the working language is English. Our research program focus on the cell biology of innate immunity and antigen presentation in response to microbes and stress. We are deciphering the novel and promising interface between translation control, metabolism and innate immunity. For further information, please contact visit our website: www.ciml.univ-mrs.fr/science/lab-philippe-pierre/experts. Research topics: Translation regulation and quality control, autophagy, ubiquitination and MHC transport.
Dendritic cells (DCs) have the unique capacity to initiate primary immune responses. We are interested in the fundamental changes occurring during the activation of DCs by pathogens (maturation). Understanding DC maturation provides new insights to how the immune response can be modulated. Our aim is to elucidate the molecular mechanisms by which DCs control antigen processing and cytokine production during pathogen detection and metabolic abnormalities. We are focusing on protein synthesis quality control in relationship to autophagy and MHC restricted antigen presentation. We are also searching for molecules regulating membrane traffic in conventional DCs and plasmacytoïd DCs. The laboratory is specialized in interdisciplinary approaches using transcriptomics, cell biological techniques and bio-imaging tools to try to meet the challenge of understanding the molecular changes occurring during DC activation.
Our institute, the CIML, is one of the leading European centers of biomedical research located in Marseille’s science park in France. We have excellent funding and core facilities, which include onsite transgenic services and in-house antibody production, together with bioinformatics, and microarray platforms. CIML is a site of excellence for confocal/bi-foton imaging and cytofluorimetry. Scientists from more than 20 countries work at the CIML. Marseille is an international and
cosmopolitan city, with very nice surroundings, close to the Alps and Mediterranean sea and 3 hours from Paris by train. Our laboratory offers competitive salaries with social benefits.We are seeking a highly motivated candidate for joining our dynamic and international team with:
- a PhD and 0-3 years of relevant postdoctoral experience.
- a strong track-record of publications in peer-reviewed journals
- experience in cell biology, immunology, biochemistry, mouse models,
signal transduction and/or cell imaging are highly desirable.
Please send your application as a single PDF document containing a cover letter, a concise summary of previous research, a Curriculum Vitae, a publication list and contact details for at least 2 references to: Philippe PIERRE & Evelina GATTI
gatti@ciml.univ-mrs.fr or pierre@ciml.univ-mrs.fr
Post-Doctoral Position, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), Switzerland
A post-doctoral position is open in the Laboratory of Innate Immunity and Septic Shock from the Infectious Diseases Service, CHUV and UNIL (www.chuv.ch and www.unil.ch).
The applicant will study the influence of macrophage migration inhibitory factor (MIF), a proinflammatory cytokine and an important mediator of innate immune responses (Nature Rev Immunol 2003;3:791), on dentritic cell (DC) ontogeny and functions. The interactions between MIF, DCs and immune responses will be examined in vitro and in animals under inflammatory and infectious conditions. The candidate will have to generate conditional MIF knockout mice with deletion of the Mif gene targeted in DCs.
The applicant should have knowledge in immunology and dendritic cells, experience with standard techniques (WB, FACS, ELISA, RT-PCR, cloning…), willingness to work with animals, and a good practice of English.
The project is supported by grants from the Swiss National Science Foundation. The salary is according to the scale of the UNIL, Switzerland. The position (one year renewable twice) is available immediately.
Send applications (letter of motivation, CV with a description of research experience, methodologies used, publication record and a list of potential references) to Thierry Calandra (+41-21-314-10-26; Thierry.Calandra@chuv.ch) or Thierry Roger (+41-21-314-10-38; Thierry.Roger@chuv.ch). Additional information on www.unil.ch/fbm/page71277_en.html and www.unil.ch/fbm/page71251.html
Senior Research Scientist – Clinical Immunology
Bristol, UK
Apitope is a world-leader in the research and development of novel therapeutic peptides to address critical unmet needs in the treatment of chronic autoimmune disorders. The company’s innovative technology has attracted significant investment and forms the basis of a research, development and commercialisation agreement with a major global pharmaceutical company.
Apitope has exciting opportunities for experienced and talented Immunologists to join the research team working to support on-going and future clinical studies in multiple sclerosis and other autoimmune diseases.
Successful applicants must have an excellent understanding of human immune assays and familiarity with working to European and UK clinical trial legislation will be an advantage. Ideally educated to PhD level you will have significant experience of working on the development and use of immunological assays as clinical endpoints.
To apply, please send a copy of your CV and brief covering letter to jobs@apitope.com not later than October 31st, 2011. All applicants must be eligible to work in the UK. No agencies please
Field Application Scientist - Molecular Diagnostics EMEA
Home office based across EMEA
Responsibilities
Support activities:
• Provide customers with support during technology and application installation.
• Troubleshooting issues (as a support to the Technical Service): answer to customer's technical inquiries, provide timely solutions to customer and distributor queries raised by e-mail or telephone ensuring they are handled and resolved in an efficient manner.
• Implementations and ongoing support of company products to ensure performance meets customer requirements
Pre- and post-sales activities to assist sales process:
• Technical presentations and demonstrations seminars or webinars and conference calls to educate our customers.
• Prepare and present audio/visual material to prospective customers, and to audiences at seminars and international conferences.
• Develop and deliver appropriate customer and distributor training programs, as well as internal training programs for engineers or any other groups as required.
• Acting as a key contributor of customer feedback to marketing and product development teams.
• International travel is an essential requirement of this role. The territory to be covered is Europe (including CIS), Middle-East and Africa.
• The FAS will belong to the Molecular Diagnostics team which includes sales and marketing people. The main focus will be primarily on HLA typing.
Candidate Requirements
• Education and experience: graduation in Molecular Biology or Biochemistry is mandatory (BA/BS, MSc, PhD) with lab experience in molecular biology or genetics. Proficiency with common molecular biology bench techniques is required. Qualification in sequencing is highly desirable. Immunology and bioinformatics knowledge would be a plus.
• Significant experience or aptitude in structured customer problem solving.
• Ability to interact with people in a positive and professional manner.
• Strong presentation or teaching skills
• Commercially aware and able to demonstrate the benefits of our products to our customers.
• Analytical, methodical and organised approach with ability to prioritise competing issues.
• Clear vision of and commitment to providing outstanding customer service
• Excellent English and French written and oral communication skills. Additional languages are a plus.
• Highly computer literate.
• Self-motivated with a flexible attitude.
• Team player
• Must be willing to travel up to 80%
• Home- office based, the applicant should be based close to an international airport with an excellent pan-European hub (direct connections)
To apply: Please apply through our website www.lifetechnologies/career Req. No. 8152BR
or email to peggy.klein@lifetech.com
New Zealand: Lecturer in Immunology; Department of Microbiology and Immunology
Applications are invited from PhD-qualified candidates for the position of Lecturer in Immunology. The Department seeks an appointee that will develop an independent research programme within the discipline of Immunology. Competence in research should be demonstrated by an appropriate publication record. The successful appointee will contribute to the academic excellence and diversity of the department through their research and teaching at undergraduate and postgraduate levels.
Specific enquiries may be directed to the Head of Department, Professor Frank Griffin, Department of Microbiology and Immunology, Tel +64 3 479 7718, Email hod.microbiology@otago.ac.nz
Applications quoting reference number 1100321 will close on Friday 12 August 2011.
APPLICATION INFORMATION
To see a full job description and to apply online go to:
www.otago.ac.nz/jobs
Equal opportunity in employment is University policy.
INDIA: THSTI-IAVI HIV Vaccine Program is seeking a Program Director to head the Program
Translational Health Science and Technology Institute (THSTI) an initiative of Department of Biotechnology, Government of India and International AIDS Vaccine Initiative (IAVI), USA are seeking a Program Director for their new joint collaborative program to accelerate and advance HIV vaccine research and development. The program shall be an integral part of the THSTI cluster of research centers and will be closely linked to global network of R&D facilities, including IAVIs Neutralizing Antibody Consortium (NAC) and IAVI Design and Development lab, situated in Brooklyn, New York. The Design Lab examines novel AIDS vaccine platforms and immunogens, standardizes preclinical testing of AIDS vaccine candidates, and develops candidates for evaluation in clinical trials
It would be an innovative discovery program and will be directed at designing, testing and implementing high-throughput (HT) strategies for HIV-1 envelope-based immunogen screening and prioritization to help discover and advance novel HIV vaccine candidates. The program is targeted to expand the number of vaccine candidates for testing, and enhance the speed with which they can be assayed. The unique industrial-type high-throughput vaccine design, screening and selection processes proposed will be largely facilitated by interdisciplinary interaction and thus driven by principles of international collaboration, high-quality science and vaccine-oriented applied research.
Key Responsibilities:
• Lead, plan, monitor, review, coordinate and guide all scientific and operational aspects of the Program, ensuring integration with THSTI’s vision and mission and the scientific agenda of IAVI’s global Neutralizing Antibody Consortium and scientific collaborators.
• Develop overall scientific plan and after their approval from the THSTI-IAVI Program Steering and Management Committee provide the program with scientific direction and ensure that the highest quality of scientific skill, diligence and rigor is applied to all projects within the Program
• Serve as a member of the Program Management Committee and report to it, regularly on progress.
• Develop key initiatives on technology mapping and sourcing plans, including establishing and managing key technology partnerships (academics, consultants, inventors and, industry) to support these efforts.
• Responsible for resource management including recruitment, budgeting and monitoring.
• Ensure and establishing effective working relationships, scientific linkages and collaborations with other scientists within THSTI cluster and IAVI NAC and also with THSTI and IAVI India office.
Key Capabilities and Experience:
The successful candidate should have a strong foundation in science and be an experienced vaccine scientist with a commitment to the design and advancement of HIV vaccines.
• S/He should be an MD or PhD in biological sciences with over 10 years of experience in HIV research, high throughput screening, immunogen design and vaccine development.
• S/He should be experienced in leading and mentoring a group of scientists, ability to manage short-term and long-term lab resource needs and facility budgets to achieve the set objectives.
• S/He should define ambitious goals and establishes priorities, designing processes and managing projects and resources that align to achieve those goals.
• S/He should be creative and flexible in approaching problem-solving and management in a globally diverse and highly matrixed environment.
• S/He should have strong written and oral communication skills and should have significant record of professional accomplishment including publications, patents and invited speaking engagements;
• S/He should be a team player and team-builder who is willing to work with and patiently align diverse stakeholders who maintain their individual autonomy and decision-making.
The position is currently based in Gurgaon, National Capital Region of Delhi, India and will be contractual basis and the compensation shall be commensurate with experience. The position will report directly to the IAVI Country Director – India, with a technical reporting line to the Vice President for Vaccine Design, in New York. The position will have 3 Principal Investigators and a Scientific Project Manager as direct reports. The program offers an enabling environment with tremendous opportunities for growth.
Interested candidates may please send in their applications with a cover note, current curriculum vitae and bibliography, together with a brief description of past and present scholarly interests and accomplishments to:
Ms. Sangeeta Sabharwal, Senior Partner, Transearch India, A – 10, Sanskrit Bhawan, Aruna Asaf Ali Marg, Qutub Institutional Area, New Delhi – 110 067, India. E-mail: iaviresponse@transearchindia.com
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